The process of gout formation and development.

Gout is a metabolic chronic disease caused by disorder of protein metabolism, which leads to excessive oxidation of total purine to uric acid. The imbalance and translocation of microflora in gastrointestinal tract caused by high protein diet preference are the initiating factors. The excessive absorption of amino acids by active and passive digestion will break the balance of nitrogen metabolism in the body. When the balance of nitrogen metabolism is broken, endogenous purine and exogenous purine are oxidized by liver to produce hyperuricemia, which leads to hyperuricemia.

In the state of disordered protein metabolism, abnormal metabolism of random liposomes and carbohydrates will lead to abnormal blood lipid and microcirculation disorders. Microcirculation disorders lead to cell metabolic disorders, and then the formation of local tissue cell necrosis and precipitated monosodium urate crystals will be converted into non-bacterial inflammatory factors, after several years of evolution, will lead to gout. In the early stage, arthritis was the main manifestation. In the middle and late stage, multiple organ injuries were involved, such as kidney stones, urethral stones and gout stones in the urinary system.

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